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Loneliness has always been around, but contemporary life makes us particularly vulnerable to it. It may relate to a particular situation, or be a deeper form of loneliness pervading a person's whole life.
Source: Mind

Medication: lithium and other mood stabilisers

This booklet is aimed at people who are taking mood stabilizing drugs, and anyone interested in learning more about them. It explains what the drugs are, their drawbacks and benefits, and how they can best be used safely and effectively for the treatment of bipolar disorder (manic depression), recurrent depression, and similar mood disorders. It also looks at ways to withdraw from them successfully.
Source: Mind
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Subject Definitions

Mood swings should not be confused with Bipolar Disorder or Manic Depression Disorder, in which extreme moods persist for weeks and months at a time. Mood swings are extremely common and there are several treatment options to help regulate a person’s mood.